Vitamins and Aging: Pathways to NAD+ Synthesis

نویسنده

  • John M. Denu
چکیده

Recent genetic evidence reveals additional salvage pathways for NAD(+) synthesis. In this issue, Belenky et al. (2007) report that nicotinamide riboside, a new NAD(+) precursor, regulates Sir2 deacetylase activity and life span in yeast. The ability of nicotinamide riboside to enhance life span does not depend on calorie restriction.

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عنوان ژورنال:
  • Cell

دوره 129  شماره 

صفحات  -

تاریخ انتشار 2007